李家平，男，江苏扬州人，中共党员，医学博士，美国南加州大学博士后，现任中山大学附属第一医院肿瘤介入科主任、教授、主任医师、博士生导师，优秀青年人才培养对象，主要从事肿瘤介入与靶向治疗。

　　医疗专长

　　擅长于肿瘤与血管疾患的微创介入治疗，特别是对原发性肝癌、转移性肝癌、肺癌、胆管癌、胰腺癌、膀胱癌、盆腔肿瘤、儿童腹部恶性实体瘤、血管瘤和血管畸形的介入诊疗(包括局部肿瘤的化疗栓塞、氩氦刀冷冻、射频、微波消融、粒子与支架植入、药盒埋置、全身规范化疗和分子靶向治疗)，并在肝硬化门脉高压症、颈动脉体瘤、外周血管闭塞性疾病、主动脉瘤及夹层腔内治疗等方面也积累了较丰富的诊疗经验。

　　社会兼职

　　现任中国医师协会介入医师分会全国青年委员会主任委员、中华放射学会介入学组青年委员、肿瘤介入专业委员会副主任委员、中国抗癌协会肿瘤微创治疗专业委员会肝癌专业分会副主任委员、影像技术分会副主任委员、粒子学组青年副主任委员、中华医学会肿瘤介入专业委员会委员、广东省医学会介入学组委员，广州抗癌协会肿瘤微创治疗专业委员会副主任委员、亚洲冷冻外科学会创始会员、亚太影像引导下肿瘤消融协会常务理事、广东省医师协会介入分会常委，教育部留学归国人员基金评审专家，教育部博士后基金评审专家，国家自然科学基金评审专家，以及Cardiovasc Intervent Radiology,Journal of Vascular & Interventional Radiology, Neurosurgery, J Urology, J Vasc Surg ，European Radiology等多家国际专业杂志的评阅人和撰稿人。

　　学术业绩

　　主持国家自然科学基金研究面上项目2项，主持省部级重大科研基金项目1项，以及包括教育部留学回国人员启动基金项目在内的省部、厅局级科研项目17项，主编介入专著1部，参编9部。在核心医学杂志上发表论文130余篇，SCI收录论著近40余篇，建立了具有较强实力与规模的肿瘤介入医学临床与研究团队。

　　2013年亚太肿瘤介入大会、2014年肝癌微创与综合治疗广州国际高峰论坛任共同执行主席。

　　研究方向

　　1. 肿瘤微创治疗的临床与基础研究

　　2. microRNA 在肝癌血管生成中的调控机制及分子影像学监测

　　3. 肝癌发生发展的分子机制;肝癌防治靶点研究

　　4. 经肝动脉导入MAT1A基因和MAT2A短发夹RNA协同抗肝癌的实验研究

　　5. 经肝动脉应用I131 chTNT联合TACE治疗中大肝癌的系列研究

　　近期论文

　　1. Fan W, Zhang Y, Wang Y, Yao X, Yang J, Li J(李家平)(通讯作者).Neutrophil-to- Lymphocyte and Platelet-to-Lymphocyte Ratios as Predictors of Survival and Metastasis for Recurrent Hepatocellular Carcinoma after Transarterial Chemoembolization. PLoS One. 2015; 10(3):e0119312.

　　2. Jiaping Li(通讯作者), Fujun Zhang, Jianyong Yang, Yingqiang Zhang, Yu Wang, Wenzhe Fan, Yonghui Huang, Wei Wang, Henry Ran, Shi Ke. Combination of individualized local control and target-specific agent to improve unrespectable liver cancer managements: a matched case-control study. Targeted Oncology. 08 Oct 2014.[Epub ahead of print]

　　3. Yi Jin, Jianning Chen, Zhiying Feng, Zhigang Zhang, Yu Wang, Wenzhe Fan, Jiaping Li(李家平)(通讯作者). OPN and αvβ3 Expression are Predictors of Disease Severity and Worse Prognosis in Hepatocellular Carcinoma. PLOS One. 2014, 3; 9(2):e87930. PMID:24498405

　　4. Jin Y,Chen J,Feng Z,Fan W, Wang Y, Li J(李家平)(通讯作者), Tong D. The expression of Survivin and NF-κB associated with prognostically worse clinicopathologic variables in hepatocellular carcinoma. Tumour biology, 05 Jul 2014[Epub ahead of print].

　　5. Fu SR, Zhang YQ, Li Y, Hu BS, He X, Huang JW, Zhan MX, Lu LG, Li JP(李家平)(通讯作者). Sorafenib continuation after first disease progression could reduce disease flares and provide survival benefits in patients with hepatocellular carcinoma: a pilot retrospective study.Asian Pac J Cancer Prev. 2014;15(7):3151-6.PMID:24815462

　　6. Jin Y, Tong D, Shen J, Yang J, Li J. (李家平)(通讯作者)Establishment of implantation tumor models of hepatocellular carcinoma in Wistar rats. Tumour Biol. 2014 Jun 7. [Epub ahead of print] PMID: 24913708

　　7. Qi Zhou, Yafeng Wang, Baogang Peng, Lijian Liang, Jiaping Li(李家平)(通讯作者).The Roles of Notch1 Expression in the Migration of Intrahepatic Cholangiocarcinoma. BMC Cancer.2013, 13:244.

　　8. Gao ZH, Yin JQ, Liu DW, Meng QF, Li JP(李家平)(通讯作者).Preoperative easily misdiagnosed telangiectatic osteosarcoma: clinical-radiologic-pathologic correlations. Cancer Imaging. 2013,11;13(4):520-6.

　　9. Junxing Chen, Zhijun Yao, Shaopeng Qiu, Lingwu Chen, Yu Wang,Jianyong Yang, Jiaping Li(李家平)(通讯作者). Comparingintra-arterial chemotherapy combined with intravesical chemotherapy versusintravesical chemotherapy alone: a randomised prospective pilot study for T1G3bladder transitional cell carcinoma after bladder-preserving surgery. Cardiovasc Intervent Radiol. 2013, 36(6)1521-1526.

　　10. Yi Jin, Da-yue Tong, Jian-ning Chen, Zhi-ying Feng, Jian-yong Yang ,Chun-kui Shao, Jia-ping Li(李家平)(通讯作者). Overexpressionof osteopontin αvβ3 and Pim-1 associated with prognostically importantclinicopatholo.PLOS One. 2012, 7(10), e48575.

　　11. Wang Yu, Lian Fan, Li Jiaping(李家平), et al. Adipose derived mesenchymal stem cells transplantation via portal vein improves microcirculation and ameliorates liver fibrosis induced by CCl4 in rats. Journal of Translational Medicine. 2012, 10(1): 133.

　　12. Chen JX, Deng N, Chen X, Chen LW, Qiu SP, Li XF, Li JP(李家平)(通讯作者).A novel molecular grading model: combination of Ki67 and VEGF in predicting tumor recurrence and progression in non-invasive urothelial bladder cancer. Asian Pac J Cancer Prev. 2012; 13(5):2229-34.

　　13. Wu J, Zhou Q, Wang Y, Zhou X, Li J(李家平)(通讯作者). MNT inhibits the migration of human hepatocellular carcinoma SMMC7721 cells. Biochem Biophys Res Commun. 2012 Feb 3; 418(1):93-7.

　　14. Qi Zhou, Yafeng Wang, Xiangbing Zhou, Baogang Peng, Jianyong Yang, Lijian Liang1, Jiaping Li(李家平)(通讯作者). Prognostic Analysis for Treatment Modalities in Hepatocellular Carcinomas with Portal Vein Tumor Thrombi. Asian Pacific J Cancer Prev, 2012, 12, 2847-2850.

　　15. Li J(李家平),Ramani K, Sun Z, Zee C, Grant EG, Yang H, Xia M, Oh P, Ko K, Mato JM, Lu SC. Forced Expression of Methionine Adenosyltransferase 1A(MAT1A)in Human Hepatoma Cells Suppresses in vivo Tumorigenicity in Mice.American Journal of Pathology, 2010, 176(5):2456-2466.

　　16. Jia-Ping Li(李家平),Jian-Ping Chu, Pilsoo Oh, Zhi Li, Wei Chen, Yong-Hui Huang, Jian-Yong Yang. Characterizing the clinicopathologic findings of transarterial chemoembolization in wilms’ tumor. J Urology, 2010, 183(3):1138-1144.

　　17. Jiaping Li(李家平), Shenming Wang, Chishing Zee, Jianyong Yang, Zhuang Wenquan, Wei Chen, Xiaoxi Li,Weiming Lv, Yonghui Huang, Songqi Li. Preoperative Angiography and Transarterial Embolizationin The Management ofCarotid Body tumor-A Single Centre 10 Years Experience. Neurosurgery, 2010, 67(4): 941-948.

　　18. Yi Jin, Jia-Ping Li(李家平)(并列第一作者), Dan He, Lu-Ying Tang, Chi-shing Zee, Shao-Zhong Guo, Jing Zhou, Jian-Ning Chen, Chun-Kui Shao. Clinical Significance of Human Telomerase RNA Gene (hTERC)Amplification in Cervical Squamous Cell Lesions Detected byFluorescence in Situ Hybridization.Asian Pacific J Cancer Prev,2012, 12, 1167-1171

　　19. J. Li(李家平), W.Fan, J. Yang, Y. Wang, W. Chen, Y. Zhang. Experimental study on the transcriptional targeting gene therapy of double suicide gene driven by hTERT promotor in hepatoma carcinoma. Journal of Vascular and Interventional Radiology.2012, 23(3) Suppl, S51-52.

　　20. J. Li(李家平),W.Fan, J.Yang,Y.Wang,W. Chen, X.Xie, M. Lu.Transcatheter arterial chemoembolization (TACE) combined percutaneous thermal ablation in large hepatocellular carcinoma: clinical observation of the efficacy and predictors of prognostic factors. Journal of Vascular and Interventional Radiology.2012, 23(3) Suppl , S19-S20.

　　21. Li JP(李家平), Chu JP, Yang JY, Chen W, Wang Y, Huang YH. Transcatheter selectively arterial chemoembolization in treatment of unresectable hepatoblastoma in infants and children. Cardiovasc Intervent Radiology, 2008, 31(6):1117-1123.

　　22. Yang H, Ko K, Xia M, Li TW, Oh P,Li J(李家平),Lu SC. Induction of avian musculoaponeurotic fibrosarcoma proteins by toxic bile acid inhibits expression of glutathione synthetic enzymes and contributes to choles- tatic liver injury in mice. Hepatology, 2010, 51(4):1291-1301.

　　23. Zhou F, Zee CS, Gong H, Shiroishi M, Li J(李家平).Differential changes in deep and cortical gray matters of patients with multiple sclerosis: a quantitative magnetic resonance imaging study. J Comput Assist Tomogr, 2010, 34(3):431-436.

　　24. Lian F, Wang Y, Chen W, Li J(李家平), Zhan Z, Ye Y, Zhu Y, Huang J, Xu H, Yang X, Liang L, Yang J.Uterine Artery Embolization Combined with Local Methotrexate and Systemic Methotrexate for Treatment of Cesarean Scar Pregnancy with Different Ultrasonographic Pattern. Cardiovasc Intervent Radiol .2011 Jan 27. Epub.

　　25. Jian-Ping Chu, Wei Chen, Jia-Ping Li(李家平), Zhuang WQ, Huang YH, Huang ZM, Yang JY. Clinicopathologic features and results of transcatheter arterial chemoembolization for osteosarcoma. Cardiovasc Inter Rad, 2007, 30:201-206.

　　26. Peng Bao-Gang, He Qiang,Li Jia-Ping(李家平),Zhou Fan. Adjuvant transcatheter arterial chemoembolization improves efficacy of hepatectomy for patients with hepatocellular carcinoma and portal vein tumor thrombus. American journal of surgery, 2009, 198(3):313-318.

　　27. Yang H, Ramani K, Li TW, Oh P, Li J (李家平), Lu SC. Dysregulation of glutathione synthesis during cholestasis in mice: molecular mechanisms and therapeutic implications. Hepatology, 2009, 49(6):1982-1991.

　　28. Yang H, Ko KS, Xia M, Li T, Oh P,Li J(李家平), Lu SC. Induction of Maf Proteins by Toxic Bile Acid Inhibits Expression of GSH Synthetic Enzymes and Contributes to Cholestatic Liver Injury in Mice" has been received by our editorial office. Hepatology, 2009, 49(6):1982-1991.

　　29. Xu HX, Liu L, Lu MD, Li HP, Liu GJ,Li JP(李家平). Three-dimensional power Doppler imaging in depicting vascularity in hepatocellular carcinoma.J Ultrasound Med, 2003, 22(11):1147-1154.

　　30. Wang S, Chang G, Li X, Hu Z, Li S, Yang J,Chen W, Li J(李家平).Endovascular treatment of arch and proximal thoracic aortic lesions. J Vasc Surg, 2008, 48(1): 64-68.

　　31. J. Li(李家平), W.Fan, J. Yang, Y. Wang, W. Chen, Y. Zhang. Experimental study on the transcriptional targeting gene therapy of double suicide gene driven by hTERT promotor in hepatoma carcinoma. Journal of Vascular and Interventional Radiology.2012, 23(3) Suppl, S51-52.

　　32. J. Li(李家平),W.Fan, J.Yang,Y.Wang,W. Chen, X.Xie, M. Lu.Transcatheter arterial chemoembolization (TACE) combined percutaneous thermal ablation in large hepatocellular carcinoma: clinical observation of the efficacy and predictors of prognostic factors. Journal of Vascular and Interventional Radiology.2012, 23(3) Suppl , S19-S20.

　　33. J. Li(李家平), J. Chu, J. Yang. Clinicopathologic Features and Results of Transarterial Chemoembolization for Nephroblastoma.Journal of Vascular & Interventional Radiology, 2008, 19(2):S128.

　　34. J. Li*,J. Chu, J. Yang Clinicopathologic Features and Results of Transarterial Chemoembolization for Nephroblastoma.European Radiology.2008, 2, 18(S1):454.

　　35. 范文哲, 张应强, 王于，姚学华，杨建勇, 李家平(通讯作者)经肝动脉化疗栓塞糖尿病的危险因素肝细胞癌诱发肝源性分析，中华医学杂志，2014，94(33)

　　36. 张应强, 杨建勇, 王于，黄勇慧，范文哲, 李家平.TACE联合索拉非尼治疗大肝癌的疗效与安全性分析，中华医学杂志， 93(13)，987-991，2013

　　37. 陈俊星, 尧智军, 丘少鹏, 陈凌武, 杨建勇, 李家平.T1G3膀胱癌保留膀胱术后动脉导管化疗联合膀胱灌注化疗的疗效分析.中华泌尿外科杂志, 2012,32(2):99-103.

　　38. 范文哲, 杨建勇，陈伟，黄勇慧，王于，张应强，李家平(通讯作者).人端粒酶启动子调控双自杀基因治疗肝癌的实验研究.中华医学杂志.2011,91(43): 3080-3085.

　　39. 金亦，邵春奎，唐录英，杨建勇，黄勇慧，李家平(通讯作者).肝细胞癌中Survivin与NF-κB蛋白的表达及其临床意义.中华医学杂志.2011,91(36): 2542-2545.

　　40. 范文哲, 杨建勇，吕明德，谢晓燕，殷晓煜，黄勇慧，匡明，李鹤平，徐辉雄，李家平(通讯作者).TACE联合经皮热消融治疗大肝癌的疗效及预后分析. 中华医学杂志.2011, 91(31): 2190-2194.

　　41. 连帆, 王于, 范文哲, 杨岫岩, 许韩师, 陈伟, 杨建勇, 李家平(通讯作者). 经肝动脉同种异体脂肪干细胞移植治疗小鼠自身免疫性肝炎模型的实验研究.中国病理生理杂志,2011,27( 7):1389-1392.

　　42. 范文哲,李家平,杨建勇,等.无法手术切除的肝细胞癌TACE与RFA治疗的Meta分析.中华普通外科学文献:电子版,2010，5(1)：62-67.

　　43. 王于, 连帆, 谭国胜, 范文哲, 向贤宏, 陈伟, 杨建勇, 李家平(通讯作者).同种异体脂肪干细胞门脉移植对大鼠纤维化肝脏的影响.中国病理生理杂志,2010,26 ( 11): 2197-2201.

　　44. 李家平,王于, 李鹤平, 杨建勇. 前列地尔对肝缺血再灌注损伤保护机制的实验研究. 中华医学杂志.2009, 12(37):3653-3633.

　　45. 李家平,王海林,黄勇慧,李鹤平，王于，谭国胜, 陈伟，杨建勇.前列地尔对肝细胞癌动脉化疗栓塞后肝血流灌注的影响。中华放射学杂志，2009,43(10),1008-1013.

　　46. 李家平, 谭国胜, 黄勇慧, 陈伟, 杨建勇. 数字减影血管造影与介入治疗在胃肠道动脉性出血中的应用价值.中华胃肠外科杂志,2009,12 (3),252-256.

　　47. 李家平,黄勇慧,李鹤平，王于，杨建勇.肝缺血再灌注损伤血流动力学的CT灌注评价.中华放射学杂志，2009,43(8),878-881.

　　48. 李家平, 陈伟, 黄勇慧, 江利, 杨建勇. 肝脏CT灌注成像测定肝有效血流量的准确性与可重复性研究. 中华放射学杂志，2007,41(1),51-54.

　　49. 李家平, 杨建勇, 李桂生, 陈伟, 庄文权, 李智, 鲁建生, 周欣. 肾母细胞瘤动脉化疗栓塞的临床病理学研究.中华放射学杂志, 2002. 07.10; 36(4):644-648.

　　50. 李家平,杨建勇,陈伟,庄文权,王建波.西罗莫司对血管平滑肌细胞胶原合成影响的实验研究.中华医学杂志.2007, 87(37):2653-2656.

　　51. 李家平,周奇,王海林,陈伟, 杨建勇.前列地尔Lipo-PGE1干预肝脏血流灌注的实验研究.中国病理生理杂志，2008，24(12):3421-3427.

　　52. 李家平,陈伟, 李智, 李桂生, 杨建勇. 肾母细胞瘤经动脉化疗栓塞术疗效机制探讨. 中国病理生理杂志,2007, 23(11):1195-1199.

　　53. 李家平, 陈伟, 黄勇慧, 江利, 杨建勇.CT灌注成像对经颈静脉肝内门体分流术(TIPSS)后肝血流灌注变化的评价.中华外科学杂志,2008，46(9):313-318 .

　　54. 李家平, 陈伟, 江利, 杨建勇.运用CT灌注成像监测介入断流术后肝脏血流灌注的变化.中华外科学杂志2007, 45(13):913-916.